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Dual-targeting RNA nanoparticles for efficient delivery of polymeric siRNA to cancer cells
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | KIM TAEHYUNG | - |
| dc.contributor.author | HANA HYUN | - |
| dc.contributor.author | Roun Heo | - |
| dc.contributor.author | KEONWOOKNAM | - |
| dc.contributor.author | KYUNGJIK YANG | - |
| dc.contributor.author | YOUNG MIN KIM | - |
| dc.contributor.author | Yoon Suk Lee | - |
| dc.contributor.author | Jae Yoon An | - |
| dc.contributor.author | Jae Hyung Park | - |
| dc.contributor.author | Ki Young Choi | - |
| dc.contributor.author | Young Hoon Roh | - |
| dc.date.accessioned | 2021-12-01T02:40:19Z | - |
| dc.date.available | 2021-12-01T02:40:19Z | - |
| dc.date.issued | 2020-06 | - |
| dc.identifier.issn | 1359-7345 | - |
| dc.identifier.uri | https://yscholarhub.yonsei.ac.kr/handle/2021.sw.yonsei/5314 | - |
| dc.description.abstract | A new dual-targeting polymeric siRNA nanoparticle (Dual-PSNP) was developed via multiple processes: rolling circle transcription, condensation, electrostatic deposition, and click chemistry. The Dual-PSNP showed significantly improved cancer-specific intracellular delivery, gene knockdown efficacy, and apoptosis-mediated cytotoxicity through additive receptor-mediated interactions of the two ligands. | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | ROYAL SOC CHEMISTRY | - |
| dc.title | Dual-targeting RNA nanoparticles for efficient delivery of polymeric siRNA to cancer cells | - |
| dc.type | Article | - |
| dc.publisher.location | 영국 | - |
| dc.identifier.doi | 10.1039/d0cc01848a | - |
| dc.identifier.scopusid | 2-s2.0-85086747115 | - |
| dc.identifier.wosid | 000543208800029 | - |
| dc.identifier.bibliographicCitation | CHEMICAL COMMUNICATIONS, v.56, no.49, pp 6,624 - 6,627 | - |
| dc.citation.title | CHEMICAL COMMUNICATIONS | - |
| dc.citation.volume | 56 | - |
| dc.citation.number | 49 | - |
| dc.citation.startPage | 6,624 | - |
| dc.citation.endPage | 6,627 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
| dc.subject.keywordPlus | PROGRESS REPORT | - |
| dc.subject.keywordPlus | IN-VITRO | - |
| dc.subject.keywordPlus | MICROSPONGES | - |
| dc.subject.keywordPlus | INTERFERENCE | - |
| dc.subject.keywordPlus | NANOCARRIERS | - |
| dc.subject.keywordPlus | CHALLENGES | - |
| dc.subject.keywordPlus | DISEASE | - |
| dc.subject.keywordAuthor | RNA nanotechnology | - |
| dc.subject.keywordAuthor | rolling circle transcription | - |
| dc.subject.keywordAuthor | siRNA | - |
| dc.subject.keywordAuthor | dual-targeting | - |
| dc.subject.keywordAuthor | cancer therapy | - |
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Related Researcher
- Kyungjik, Yang
- College of Life Science and Biotechnology (Biotechnology)