Synthesis of Poly-Substituted Imidazo[1,2-a]Pyridines via a Double Annulation Strategy
  • Jung, Myungho
  • Lee, Sunhee
  • 구도희
  • Kang, Dageum
  • Kim, Ikyon

초록

A highly efficient domino process consisting of conjugatesubstitution, nucleophilic addition, and cycloisomerization fromthe reaction of enaminonitrile with propargylamine allowed for asuccessive double ring closure to afford a densely functionalizedimidazo[1,2-a]pyridine through formation of three C─N bonds.

제목
Synthesis of Poly-Substituted Imidazo[1,2-a]Pyridines via a Double Annulation Strategy
저자
Jung, MyunghoLee, Sunhee구도희Kang, DageumKim, Ikyon
DOI
10.1002/ajoc.70175
발행일
2025-11
저널명
Asian Journal of Organic Chemistry
14
11