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Regioselective double dehydrative cyclization route to construct polyheterocyclic skeletons consisting of 2,3-dihydroquinazolin-4(1H)-ones and 1,2-dihydropyrrolo[1,2-a]pyrazines
- 구도희;
- Song, Seoyoung;
- Kim, Ikyon
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0초록
The Sc(OTf)3-catalyzed reaction of 2-aminobenzamide with N-substituted pyrrole-2-carboxaldehyde proceeded well to give a tetracyclic skeleton consisting of dihydroquinazolin-4-one and 1,2-dihydropyrrolo[1,2-a]pyrazine via regioselective double cyclodehydrations where two heterocyclic rings (quinazolinone and pyrazine) were sequentially constructed through the formation of three C-N bonds.
- 제목
- Regioselective double dehydrative cyclization route to construct polyheterocyclic skeletons consisting of 2,3-dihydroquinazolin-4(1H)-ones and 1,2-dihydropyrrolo[1,2-a]pyrazines
- 저자
- 구도희; Song, Seoyoung; Kim, Ikyon
- 발행일
- 2025-07
- 권
- 23
- 호
- 27
- 페이지
- 6589 ~ 6602