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Screening of Pancreatic Ribonuclease A Inhibitors from an Autodisplayed Fv-Antibody Library

Authors
성정수Jung, JaeyongHwang, HyeminBong, Ji-HongKang, Min-JungJose, JoachimLee, MisuPyun, Jae-Chul
Issue Date
Dec-2023
Publisher
American Chemical Society
Citation
ACS Pharmacology and Translational Science, v.6, no.12, pp 1945 - 1957
Pages
13
Journal Title
ACS Pharmacology and Translational Science
Volume
6
Number
12
Start Page
1945
End Page
1957
URI
https://yscholarhub.yonsei.ac.kr/handle/2021.sw.yonsei/23342
DOI
10.1021/acsptsci.3c00232
ISSN
2575-9108
Abstract
Pancreatic ribonuclease A (RNase A) inhibitors were screened from an autodisplayed Fv-antibody library, which was prepared by randomizing amino acid sequences of the third complementary-determining region (CDR3) within the heavy chain variable region (V
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공과대학 (공과대학 신소재공학과)
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