Detailed Information

Cited 1 time in webofscience Cited 0 time in scopus
Metadata Downloads

Gelatin MAGIC powder as nutrient-delivering 3D spacer for growing cell sheets into cost-effective cultured meat

Authors
SOHYEONPARKSUNGWONJUNGMOONHYUN CHOIMILAELEEBUMGYU CHOIWon-Gun KohSangmin LeeJINKEE HONG
Issue Date
Nov-2021
Publisher
ELSEVIER SCI LTD
Keywords
Gelatin microsphere; Structural modification; 3D functional carrier; Mass proliferation; Cell sheet
Citation
BIOMATERIALS, v.278, pp.121155-1 - 121155-11
Journal Title
BIOMATERIALS
Volume
278
Start Page
121155-1
End Page
121155-11
URI
https://yscholarhub.yonsei.ac.kr/handle/2021.sw.yonsei/5267
DOI
10.1016/j.biomaterials.2021.121155
ISSN
0142-9612
Abstract
Cell cultured meat is artificial meat obtained by culturing animal-derived cells in vitro, and received significant attention as an emerging future protein source. The mass proliferation of cells in the cultured meat production is a strenuous process that delays the commercialization of cultured meat because it requires an expensive culture medium for a long period. Herein, we report on a strategy to develop advanced cultured meat using fish gelatin mass growth-inducing culture (MAGIC) powder and myoblast sheets. The MAGIC powder had an edible gelatin microsphere (GMS) structure and exhibited different morphologies and bonding activities depending on the degree of crosslinking. We analyzed the loading and release of nutrients for each GMS with diverse surface properties, and selected the most effective GMSs to improve the proliferation of myoblasts under serum-reduced medium. The GMSs exerted four significant functions in the culture of myoblast sheets, and consequently produced cost- and time-effective meat-like cell sheets than the conventional method. We prepared cultured meats composed of cell sheet containing GMSs and evaluated the quality of the cultured meat by comparing the tissue properties with soy meat and chicken breast.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Engineering > Chemical Engineering > 1. Journal Articles

qrcode

Items in Scholar Hub are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher ,  photo

,
College of Engineering (Chemical Engineering)
Read more

Altmetrics

Total Views & Downloads

BROWSE