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Application of nanomaterials as an advanced strategy for the diagnosis, prevention, and treatment of viral diseases

Authors
JONG-WOO LIMAhn Y.-R.GEUNSEON PARKKim H.-O.SEUNGJOO HAAM
Issue Date
Oct-2021
Publisher
Multidisciplinary Digital Publishing Institute (MDPI)
Keywords
nanomaterials; viral diseases; vaccines; diagnosis
Citation
Pharmaceutics, v.13, no.10, pp.1570-1 - 1570-28
Journal Title
Pharmaceutics
Volume
13
Number
10
Start Page
1570-1
End Page
1570-28
URI
https://yscholarhub.yonsei.ac.kr/handle/2021.sw.yonsei/5268
DOI
10.3390/pharmaceutics13101570
ISSN
1999-4923
Abstract
The coronavirus disease (COVID-19) pandemic poses serious global health concerns with the continued emergence of new variants. The periodic outbreak of novel emerging and re-emerging infectious pathogens has elevated concerns and challenges for the future. To develop mitigation strategies against infectious diseases, nano-based approaches are being increasingly applied in diagnostic systems, prophylactic vaccines, and therapeutics. This review presents the properties of various nanoplatforms and discusses their role in the development of sensors, vectors, delivery agents, intrinsic immunostimulants, and viral inhibitors. Advanced nanomedical applications for infectious diseases have been highlighted. Moreover, physicochemical properties that confer physiological advantages and contribute to the control and inhibition of infectious diseases have been discussed. Safety concerns limit the commercial production and clinical use of these technologies in humans; however, overcoming these limitations may enable the use of nanomaterials to resolve current infection control issues via application of nanomaterials as a platform for the diagnosis, prevention, and treatment of viral diseases.
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