Temperature-Corrected Fluidic Glucose Sensor Based on Microwave Resonator

Abstract

In this paper, a fluidic glucose sensor that is based on a complementary split-ring resonator (CSRR) is proposed for the microwave frequency region. The detection of glucose with different concentrations from 0 mg/dL to 400 mg/dL in a non-invasive manner is possible by introducing a fluidic system. The glucose concentration can be continuously monitored by tracking the transmission coefficient S-21 as a sensing parameter. The variation tendency in S-21 by the glucose concentration is analyzed with equivalent circuit model. In addition, to eradicate the systematic error due to temperature variation, the sensor is tested in two temperature conditions: the constant temperature condition and the time-dependent varying temperature condition. For the varying temperature condition, the temperature correction function was derived between the temperature and the variation in S-21 for DI water. By applying the fitting function to glucose solution, the subsidiary results due to temperature can be completely eliminated. As a result, the S-21 varies by 0.03 dB as the glucose concentration increases from 0 mg/dL to 400 mg/dL.